Tibial Nerve branch to EDL - YFP Mouse 4 days after nerve crush.

Some axons are regenerating Growth cone may just be seen
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Growth cone in above image 100X confocal
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These growth cones were regenerating in vivo.  The Filopodia exist in the 3-dimensional volume.  This is in contrast to the more common view of regenerating axons, which are typically tissue cultured on a flat substrate.